having such a great effect on you that you feel confused and do not know how to react

难以抗拒的，令人不知所措的:

an overwhelming sense of guilt

一阵巨大的内疚感

She felt an overwhelming desire to hit him.

她有一种难以克制的想要揍他的欲望。

She found the city quite overwhelming when she first arrived.

她初来时觉得这座城市让她不知所措。

very large or greater, more important etc than any other

巨大的，压倒性的:

There is overwhelming evidence that smoking damages your health.

有难以辩驳的证据说明吸烟有损健康。

An overwhelming majority of the members were against the idea.

占压倒性多数的成员反对这项主张。

The proposal has been given overwhelming support.

这一提议得到了极大的支持。

The British Air Force succeeded despite overwhelming odds against them.

英国皇家空军虽然机会渺茫，但还是取得了胜利。

Congress voted overwhelmingly in favor of the bill.

国会表决时，这项提案得到压倒性的支持。