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1 .This is Scientific American's 60-Second Science. I'm Wayt Gibbs. Got a minute?
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2 .A routine CAT-scan turns up a suspicious spot.
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3 .Is it a benign lump? Or a cancerous tumor?
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4 .In the case of lung spots, four out of five turn out to be harmless.
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5 .Unfortunately, making that determination takes a long needle and a biopsy,
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6 .which means a puncture wound in the chest and a risk of infection.
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7 .Leroy Hood and colleagues at Seattle's Institute for Systems Biology have devised a painless blood test that could eliminate the need for most biopsies.
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8 .They identified 371 proteins that coat lung tumors or leak out of them.
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9 .Then they looked at blood samples taken from people who had had lung biopsies.
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10 .A pattern emerged: 13 proteins were significantly higher or lower in patients who had lung cancer than in those whose lumps were benign.
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11 .The researchers tried the blood test on different patients, and found that when it gave an "all-clear" result, it was correct 90% of the time.
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12 .The work appears in the journal Science Translational Medicine.
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13 .Indi, a diagnostics maker, is commercializing the blood test.
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14 .Hood says the same approach should work for almost any disease,
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15 .which could make diagnostics much less prickly.
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16 .Thanks for the minute, for Scientific American 60-Second Science. I'm Wayt Gibbs.
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