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This is Scientific American's 60-Second Science. I'm Karen Hopkin. This'll just take a minute.

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Hey, do you know how to get to Carnegie Hall? Practice, man!

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You might also want to switch on your alpha-synuclein gene, and throw in a dual-specificity phosphatase or two.

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Because a new study finds that these and other genes are activated when professional musicians strut their stuff.

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The findings are in the journal Nature Scientific Reports.

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Mastering an instrument is no easy feat.

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It requires timing, coordination, emotional interpretation and an ability to integrate information that comes in through the ears, the eyes and the fingers.

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But what gives rise to musical ability, biologically speaking?

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To find out, researchers took blood samples from 10 professional musicians before and after they played a selection of pieces by Stravinsky, Haydn, Mozart, and Bach.

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And they identified all of the genes that were turned on during the performance,

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that is, those genes that actually got transcribed into RNAs that could be used to make proteins.

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What they saw was a boost in the activity of genes involved in neural growth and flexibility, which could account for musicians' brains being good at forging new connections.

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Genes involved in motor control were also revved up, as were those that light up the brain's pleasure center.

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Perhaps not surprisingly, versions of about a third of these musically important genes are known to also be active in songbirds, another creature whose livelihood depends on using musical talent to wow an audience.

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Thanks for the minute, for Scientific American's 60-Second Science. I'm Karen Hopkin.

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