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This is Scientific American 60-Second Science. I'm Sophie Bushwick. Got a minute?

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Rodents are the workhorses of biomedical labs.

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So it's important to know if they're stressed out, which could affect results.

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Now we know that lab rodents may be regularly exposed to a big stressor: men.

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Researchers noticed that mice showed a lower pain response, a sign of stress, when a human was present.

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So they put mice and rats into clear cubicles, where their faces were visible, and injected them with an irritant.

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The rodents expressed pain through grimacing when no humans were nearby.

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But when confronted with a male researcher, or even just his odoriferous T-shirt, the animals grimaced less.

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Female observers did not get the same rodent reaction.

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Turns out that smelling a human male made rodents produce higher levels of a stress hormone and increase their body temperature.

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That stress response also blunted their sensitivity to pain.

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The study is in the journal Nature Methods.

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Researchers may have to come up with ways to ward off the stress effects of male researchers.

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Because to a rodent, men smell like hell.

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Thanks for the minute, for Scientific American 60-Second Science. I'm Sophie Bushwick.

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