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This is Scientific American 60-Second Science. I'm Christopher Intagliata. Got a minute?
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If you like to wind down with a drink, you've perhaps also rationalized the act with this often repeated claim:
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"You don't have to feel guilty about imbibing a little red or white: in small amounts it is good for your heart."
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But a new study finds that alcohol's supposed benefit may in fact only be available to certain people who happen to have the right genes.
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Researchers studied 600 Swedish men and women with heart disease, and compared them to some 3,000 healthy volunteers.
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They asked the subjects about their drinking, measured their blood cholesterol, and sequenced each subject's version of a gene that governs the transport of cholesterol to the liver.
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Turns out, moderate drinking, a couple of drinks a day appeared to lower heart disease risk overall by 20 percent.
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But subjects who had a specific variant of that cholesterol transport gene, and tipped back a few?
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They had an 80 percent reduction in heart disease risk.
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And the gene variant isn't protective by itself; only when combined with booze.
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The results appear in the journal Alcohol.
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Unfortunately, only about 15 percent of us have this variant.
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Study author Dag Thelle, of the University of Gothenburg, says that past studies which found what looks statistically like a slight heart benefit of moderate drinking in large populations, could actually just be detecting this huge alcohol benefit, in the small, lucky gene group.
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While the vast majority of drinkers get no benefit at all.
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So any message here for drinkers?
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"In my view there is not. Not at this time. It's far too early to say anything."
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The study's too small, he says, and has to be repeated.
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However, "Most of my friends they claim they drink moderately.
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But when I look at them I see there's quite a large variation."
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Before you order that next round, you might wanna take that idea to heart.
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Thanks for the minute, for Scientific American 60-Second Science. I'm Christopher Intagliata.
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1 / 21
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显示原文 =This is Scientific American 60-Second Science. I'm Christopher Intagliata. Got a minute?
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2 / 21
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显示原文 =If you like to wind down with a drink, you've perhaps also rationalized the act with this often repeated claim:
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3 / 21
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显示原文 ="You don't have to feel guilty about imbibing a little red or white: in small amounts it is good for your heart."
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4 / 21
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显示原文 =But a new study finds that alcohol's supposed benefit may in fact only be available to certain people who happen to have the right genes.
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5 / 21
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显示原文 =Researchers studied 600 Swedish men and women with heart disease, and compared them to some 3,000 healthy volunteers.
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6 / 21
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显示原文 =They asked the subjects about their drinking, measured their blood cholesterol, and sequenced each subject's version of a gene that governs the transport of cholesterol to the liver.
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7 / 21
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显示原文 =Turns out, moderate drinking, a couple of drinks a day appeared to lower heart disease risk overall by 20 percent.
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8 / 21
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显示原文 =But subjects who had a specific variant of that cholesterol transport gene, and tipped back a few?
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9 / 21
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显示原文 =They had an 80 percent reduction in heart disease risk.
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10 / 21
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显示原文 =And the gene variant isn't protective by itself; only when combined with booze.
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11 / 21
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显示原文 =The results appear in the journal Alcohol.
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12 / 21
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显示原文 =Unfortunately, only about 15 percent of us have this variant.
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13 / 21
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显示原文 =Study author Dag Thelle, of the University of Gothenburg, says that past studies which found what looks statistically like a slight heart benefit of moderate drinking in large populations, could actually just be detecting this huge alcohol benefit, in the small, lucky gene group.
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14 / 21
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显示原文 =While the vast majority of drinkers get no benefit at all.
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15 / 21
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显示原文 =So any message here for drinkers?
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16 / 21
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显示原文 ="In my view there is not. Not at this time. It's far too early to say anything."
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17 / 21
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显示原文 =The study's too small, he says, and has to be repeated.
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18 / 21
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显示原文 =However, "Most of my friends they claim they drink moderately.
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19 / 21
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显示原文 =But when I look at them I see there's quite a large variation."
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20 / 21
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显示原文 =Before you order that next round, you might wanna take that idea to heart.
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21 / 21
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显示原文 =Thanks for the minute, for Scientific American 60-Second Science. I'm Christopher Intagliata.
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