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This is Scientific American's 60-Second Science. I'm Karen Hopkin. This'll just take a minute.

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Exercise is good for you.

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Antioxidants are good for you.

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But put them together and it's not as good as you'd think.

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Because a recent study shows that some vitamins block the beneficial effects of exercise.

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A good workout not only gets your heart pumping, it makes your body better able to process glucose and decreases your risk of diabetes.

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And it does so, in part, by firing up your cells' mitochondria.

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Stoking those mitochondrial flames boosts your metabolism.

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But it also throws off so-called free radicals, which are usually considered harmful.

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So adding antioxidants--which get rid of free radicals--should make your workout even healthier, right?

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Well, no.

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Forty men took part in a four-week training program.

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Half the group also received daily doses of Vitamins C and E.

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The researchers discovered that exercise on its own improves insulin sensitivity, which keeps diabetes at bay.

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But taking the vitamins erased that gain--findings that appear in the May 12th issue of the Proceedings of the National Academy of Sciences.

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So you actually need a burst of potentially damaging radicals to reap some of the important rewards of a good sweat.

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Which means that even on a molecular level: no pain, no gain.

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Thanks for the minute, for Scientific American's 60-Second Science. I'm Karen Hopkin.

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