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This is Scientific American 60-Second Science. I'm Cynthia Graber. This'll just take a minute.

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The messages doctors give can influence some treatments' effectiveness.

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For example, it seems that information from a doctor affects outcomes for migraine sufferers, whether they got a real drug or a placebo.

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Researchers studied 66 people with recurring migraines over the course of seven attacks.

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During the first headache, the patients received no treatment.

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For the next six, they were given either a placebo or a drug.

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Each time, regardless of which they got, some were told it was the drug, some were told it was the placebo,

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and the rest were informed that it could be either the drug or the placebo.

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Overall, the drug did work better than the placebo.

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But the placebo worked, too, both when the patients were told it was a placebo, and even better when the doctors told them that they were getting the drug.

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That is, when the docs set their expectations high.

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Meanwhile, the actual drug was least effective when the patients thought it was a placebo.

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The study is in the journal Science Translational Medicine.

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The physician's input thus plays a role in how migraine patients fare.

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Tell them they're getting a good treatment, and they're apparently more likely to respond.

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Thanks for the minute, for Scientific American 60-Second Science. I'm Cynthia Graber.

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