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1 .This is Scientific American's 60-Second Science. I'm Karen Hopkin. This'll just take a minute.
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2 .Think about the tools used by biologists.
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3 .Perhaps test tubes and microscopes come to mind.
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4 .But what about diapers?
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5 .No, it's not that investigators are too engrossed in their work to take bathroom breaks.
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6 .Turns out the absorbent material in disposable diapers can be used to physically expand biological specimens, and make them easier to see with a microscope.
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7 .Researchers at MIT wanted to take a closer look at the connections that form between neurons in an intact brain, close enough so they could see the actual molecules those nerve cells use to interact.
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8 .That level of detail is beyond the resolution of conventional light microscopes.
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9 .But what if the structures of interest could somehow be made bigger?
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10 .That's where the diapers come in.
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11 .Researchers found that they could infuse their tissue samples with acrylate, the super-absorbent stuff in throwaway diapers.
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12 .The chemical forms a molecular mesh to which the tissue can anchor.
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13 .Then, when the researchers add water, the acrylate swells.
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14 .And so does the sample, which makes minute structures more visible.
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15 .The technique is described in the journal Science.
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16 .The researchers have used the acrylate swelling or Huggies enhancement or even Pampers amplification, if you will to peer into the brains of mice, fruit flies and zebrafish.
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17 .Now, whether this nifty nappie maneuver will expand our understanding of life¡¯s smallest cellular mysteries¡ well, Depends.
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18 .Thanks for the minute, for Scientific American's 60-Second Science. I'm Karen Hopkin.
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