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1 .This is Scientific American 60-Second Science. I'm Christopher Intagliata. Got a minute?
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2 .If you're serious about fitness, you know the importance of training your muscles and your brain.
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3 .Without the right prep, you won't have the physical or mental endurance to finish, whether it's a 5k or an Ironman.
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4 .But it turns out that it may be just as important to train your gut—or suffer inflammatory consequences.
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5 .So says a study in the International Journal of Sports Medicine.
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6 .Researchers sampled the blood of 17 runners before and after a 24-hour ultramarathon—where runners covered anywhere from 75 to 130 miles on foot.
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7 .During the race, their guts got leaky, due to a lack of blood flow to the intestines, and the physical trauma from so many jarring miles.
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8 .Gut bacteria escaped into the blood, where some released toxins.
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9 .The runners' bodies then responded by launching an immune response, and inflammation set in.
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10 .Some runners actually had blood profiles identical to those of patients admitted to the hospital with blood poisoning, or sepsis.
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11 .But the most well-trained competitors avoided the problem.
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12 .Their bodies launched a counterattack, unleashing anti-inflammatory compounds to tamp down their bodies' immune overreaction.
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13 .The authors say just four hours of activity is extreme enough to kick off this chain of inflammation.
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14 .Suggesting it's key to gradually build up to new personal bests, even if they're not ultra-worthy.
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15 .As has long been said: slow and steady wins the race.
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16 .Thanks for the minute, for Scientific American 60-Second Science. I'm Christopher Intagliata.
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